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Bone Health Glossary · Fractures & procedures

Pathologic fracture

Also called: pathological fracture

Evidence
§ Standard Definition
Topic
Fractures & procedures
Entry
Bone Dictionary
In plain English

What it means

A pathologic fracture is a bone break caused by an underlying disease weakening the bone, not by a major injury or trauma.

Why it matters for your bones

If your bone breaks easily, it may mean an underlying condition like osteoporosis or another disease needs to be found and addressed.

A pathologic fracture happens when a bone breaks because it was already weak, rather than from a hard fall or big impact. Osteoporosis is a common cause, but other things can weaken bone too, including bone metastases, multiple myeloma, Paget's disease, osteomalacia, or benign bone cysts. The break may happen during normal activities like turning, lifting, or stepping off a curb.

Doctors usually investigate why the bone broke, not just fix the break itself. This can mean imaging, blood tests, or sometimes a bone biopsy to find the underlying cause. Treatment depends on what's driving the weakness — it might involve stabilizing the bone surgically and also addressing the disease behind it, such as cancer treatment or osteoporosis medication, decided by the treating doctors.

Pathologic fractures are a signal that something deeper needs attention. If you break a bone without a clear, forceful cause, it's worth asking your doctor whether an underlying condition should be ruled out, since catching it early can guide better long-term care.

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✦ The aha

An easy bone break can signal an underlying disease, not just bad luck.

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Where this leads

305 discoveries so far
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If disease can weaken bone enough to cause a break, what's the most common one behind this? See how osteoporosis throws off the balance of bone building and breakdown.

Osteoporosis
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Related words

Fragility fracture
Strong Clinical Evidence

A fragility fracture is a broken bone caused by a fall or bump that normally wouldn't break a healthy bone, often at…

Bone metastases
Established Science

Bone metastases occur when cancer spreads from elsewhere in the body into bone, disrupting the normal balance…

Multiple myeloma
Established Science

Multiple myeloma is a cancer of plasma cells in the bone marrow that disrupts the normal bone rebuilding process,…

Paget's disease
Established Science

Paget's disease is a condition where bone remodeling speeds up too much in specific spots, creating new bone that's…

Osteomalacia
Established Science

Osteomalacia is softening of the bones caused by severe, long-term vitamin D deficiency, which prevents bone from…

Osteoporosis
Established Science

Osteoporosis is a condition where bone breakdown outpaces bone building, causing bones to become thinner, more…

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