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Bone Health Glossary · Hormones

Perimenopause

Also called: peri-menopause, perimenopausal, the change before menopause

Evidence
§ Standard Definition
Topic
Hormones
Entry
Bone Dictionary
In plain English

What it means

Perimenopause is the hormonal transition phase leading up to menopause, when estrogen levels fluctuate and periods become irregular.

Why it matters for your bones

Bone loss can quietly begin during perimenopause as estrogen starts to decline, so this is a good time to pay attention to bone health.

Perimenopause is the transition time before your final period, often starting in your 40s and lasting several years. Hormone levels, especially estrogen, start to swing up and down and gradually trend lower. Periods become irregular, and you may notice hot flashes, sleep changes, or mood shifts well before menopause is officially reached.

This hormonal shakeup matters for bone because estrogen helps keep bone breakdown in check. As estrogen levels become unpredictable and begin declining, bone turnover can start to increase even before your last period, meaning some bone loss may begin during perimenopause rather than waiting until menopause itself.

Because bone loss can start quietly during this phase, it's a reasonable time to talk with your doctor about baseline bone health, especially if you have other risk factors like a family history of osteoporosis or low body weight. A doctor can help decide if any testing or monitoring makes sense for you.

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✦ The aha

Bone loss can quietly start during perimenopause, well before periods fully stop.

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Where this leads

310 discoveries so far
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If bone loss starts as estrogen declines, what exactly does estrogen do for bone? It keeps bone-removing cells in check, so falling levels speed up loss.

Estrogen
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