← Questions/Medications and hormones
Bone health questions, answered

Do I still need my osteoporosis medication if I'm doing OsteoStrong?

Evidence
✓ Established Science
Topic
Medications and hormones
Full lesson
Tier 2 · Lesson 7
The short answer

Here's the point

That's a decision for you and your prescriber, not something OsteoStrong changes. Medication and mechanical loading work on different parts of the same system — your drug manages the chemical signalling of bone remodeling, while loading supplies a mechanical stimulus along with muscle, balance and coordination. They're meant to work alongside each other, not replace one another.

Osteoporosis medications generally fall into two families. Antiresorptives, like bisphosphonates (alendronate, risedronate, zoledronic acid) and denosumab, work by suppressing osteoclasts so the bone-removal side of remodeling slows down and formation can catch up. Anabolic agents, like teriparatide, abaloparatide, and romosozumab, do the opposite — they stimulate osteoblasts to actively build new bone. Knowing which family your medication belongs to helps you understand what it's designed to do.

Many people doing OsteoStrong are on a bone medication, and many aren't — both are welcome, and nobody is asked to change their prescription one way or the other. Loading addresses something medications don't directly provide: a mechanical signal to the skeleton, plus support for muscle, balance, and coordination, which matters because most fractures start with a fall.

If you're on a medication long-term, it's worth keeping up with monitoring and letting your prescriber know about anything else you're doing, including supplements, since some interact with osteoporosis drugs, blood thinners, or thyroid medication. Your doctor is best placed to weigh your bone density results, fracture risk, and how long you've been on a given drug.

Ultimately, whether to continue, adjust, or stop any osteoporosis medication is entirely a conversation between you and your physician. Nothing about participating in mechanical loading changes that decision-making process.

Words in this answer

Know these words

Antiresorptive
Established Science

Antiresorptive medications, like bisphosphonates and denosumab, slow down the cells that break down old bone,…

Anabolic bone agent
Strong Clinical Evidence

Anabolic bone agents are medications, like teriparatide, abaloparatide, and romosozumab, that stimulate the body to…

Bisphosphonate
Strong Clinical Evidence

Bisphosphonates are osteoporosis medications — like alendronate, risedronate, and zoledronic acid — that slow down…

Denosumab
Strong Clinical Evidence

Denosumab (Prolia) is a twice-yearly injection that blocks RANKL, a signal osteoclasts need to mature, slowing bone…

Osteogenic loading
Strong Clinical Evidence

Osteogenic loading means applying brief, high, muscle-generated force to your skeleton in a way that's strong enough…

Fall risk
Established Science

Fall risk is how likely you are to fall, and it matters because falling—not just weak bones—is the most common cause…

Evidence

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The research behind this
Established Science

Graded Established Science: Supported by broad scientific consensus and decades of research. Read each study with its grade in mind. One study is a piece of the picture, not the whole of it.

3 peer-reviewed studies, free with an Academy login
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More on medications and hormones

Bone medications generally work in one of two ways: they either slow down the cells that break down old bone (antiresorptives), or they actively stimulate the cells that build new bone (anabolics). Which family your drug belongs to tells you a lot about what it can realistically do, and that's worth asking your prescriber about directly.

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Stopping Prolia (denosumab) isn't a neutral event. Because it doesn't build up in your bones the way bisphosphonates do, its protective effect wears off once doses stop. This can lead to a rapid rebound in bone turnover and a risk of multiple vertebral fractures, sometimes within months — so this is a decision to make with your prescriber, not on your own.

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Yes, it's possible — a number of common medications can affect bone, so it's a smart question to ask. This doesn't mean you should change anything on your own; it just means it's worth reviewing your full medication list with your prescriber to understand whether bone monitoring makes sense for you.

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Whether hormone therapy is right for your bones is a decision only you and your prescriber can make, based on your personal history — but it's worth knowing the evidence on hormones and bone is actually strong and has often been misrepresented, which is likely why your doctor is being careful. The caution usually traces back to one 2002 trial that was widely misreported; since then, the understanding has shifted considerably, especially around a woman's age and timing when therapy starts.

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Have a question that isn't here? Ask us at your next visit, or ask our AI bone health advisor.

Education only, not medical advice. Decisions about tests, medications and treatment belong with your own doctor. OsteoStrong does not diagnose, treat or cure any disease.

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