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Bone Health Glossary · Hormones

Andropause

Also called: male menopause, low testosterone aging

Evidence
◆ Strong Clinical Evidence
Topic
Hormones
Taught in
Tier 3 · Lesson 4
In plain English

What it means

Andropause is the gradual, age-related decline in testosterone levels in men, sometimes called male menopause, which can affect energy, muscle, and bone strength.

Why it matters for your bones

Lower testosterone with age can weaken bone-building activity, raising the risk of bone loss and fractures in men.

Andropause describes the gradual drop in testosterone that happens as men get older. Unlike menopause, which happens over a few years, this decline is usually slow and uneven, so some men notice more effects than others. Lower testosterone can affect energy, muscle, mood, and bone strength, since testosterone helps stimulate bone-building cells and supports muscle mass that protects bones.

Bone needs a steady hormone signal to stay strong. When testosterone drops, bone remodeling can tip toward more breakdown than buildup, which over time may contribute to male osteoporosis, especially when combined with low muscle mass or inactivity. This is one reason bone loss isn't just a 'women's issue' as men age.

General healthy habits, like regular weight-bearing exercise and resistance training, getting enough protein, keeping a healthy body weight, and limiting alcohol, are often part of an overall approach to bone and hormone health, though they are not a treatment or cure for osteoporosis. If you're noticing symptoms of low testosterone, your doctor can check levels and discuss whether further evaluation or treatment, including testosterone replacement therapy, makes sense for your situation.

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Evidence

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Strong Clinical Evidence

Graded Strong Clinical Evidence: Supported by multiple well-designed clinical studies in humans. Read each study with its grade in mind. One study is a piece of the picture, not the whole of it.

2 peer-reviewed studies, free with an Academy login
✦ The aha

Declining testosterone with age can quietly weaken bone-building activity, raising fracture risk in men.

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Where this leads

15 discoveries so far
Word

Curious why falling testosterone hurts bones? Low testosterone often works indirectly, through its conversion into the estrogen your skeleton relies on most.

Low testosterone
Take me there Strong Clinical Evidence
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Where the Academy teaches it

This page is the short version. The lessons teach it in full, with the context around it and a quiz to lock it in.

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